Finding solutions in a dish

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Scope

Several groundbreaking discoveries in the past decades have contributed to the exponential increase of in vitro models’ relevance in both fundamental and translational research. In 2007, the possibility of reprograming patient-specific somatic cells into (induced) pluripotent stem cells (iPSCs) established the beginning of a new era of in vitro disease modeling studies. The additional development of versatile gene editing tools (e.g., CRISPR/Cas9), biocompatible and biomimetic biomaterials, microfluidics based culture platforms and dynamic culture systems (i.e. bioreactors) have added further complexity to these models. The present course was designed to provide a multidisciplinary discussion environment, mainly dedicated to the use of these innovative strategies and their application in the disease modeling field. For that, we will bring together national and international experts from these different backgrounds to provide students and external participants knowledge on:

Stem cell biology, particularly focused on iPSCs;
Embryonic development process and how is it recapitulated in vitro for obtaining the desired cell types from iPSCs;
Modern gene editing tools and their application in disease modeling context;
2D and 3D culture systems and how can they be modulated to improve cell maturation;
In vitro modeling studies as a tool for understanding organ-specific development and disease mechanisms.

Moreover, we will promote discussion on the advances and future challenges of these advanced in vitro models to support the replacing, reducing, and refining (3Rs) of the use of in vivo experimentation.

This course does not provide credentials for the exercise of medicine for those without appropriate training, recognition and registered at the "Ordem dos Médicos" or international equivalent institutions.

Organization

Ana Marote
Life and Health Sciences Research Institute (ICVS)
School of Medicine
University of Minho

António Salgado
Life and Health Sciences Research Institute (ICVS)
School of Medicine
University of Minho

Faculty

Alvaro Mata
Department of Chemical & Environmental Engineering, University of Nottingham, Nottingham, United Kingdom
School of Pharmacy, University of Nottingham, Nottingham, United Kingdom
Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom

Ana Marote
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Ana Ribeiro
Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
Instituto de Histologia e Biologia do Desenvolvimento, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal

António Salgado
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Carles Calatayud Aristoy
VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium
KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven, Belgium

Catarina Brito
iBET, Instituto de Biologia Experimental e Biológica, Oeiras, Portugal
Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal

Cristina Barrias
i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal

Daniel Ferreira
i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal

James Philips
Department of Biomaterials & Tissue Engineering, UCL Eastman Dental Institute, University College London, London, United Kingdom
UCL Centre for Nerve Engineering, London, United Kingdom
Department of Pharmacology, UCL School of Pharmacy, University College London, London, United Kingdom

Jens Schwamborn
Developmental and Cellular Biology, Luxembourg Center for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg

Jimena Andersen
Department of Human Genetics, Emory School of Medicine, Atlanta, USA

José Belo
Stem Cells and Development Laboratory, CEDOC, Chronic Diseases Research Centre, NOVA Medical School, Universidade Nova de Lisboa, Lisbon, Portugal

José Bragança
ABC-RI, Algarve Biomedical Center Research Institute, Faro, Portugal

Laurent Roybon
MiND iPSC Platform, Van Andel Institute, Grand Rapids, MI, USA

Magda Castelhano-Carlos
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Meritxell Pons
Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, Barcelona, Spain

Paul Wieringa
Complex Tissue Engineering Department, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, the Netherlands

Pedro Ferreira
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Pedro Rifes
Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark
The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen, Denmark

Ramiro Almeida
Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal
Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Aveiro, Portugal

Susana Rosa
Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal

Thomas Hartung
Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD, 21205, USA
CAAT-Europe, University of Konstanz, Konstanz, Germany

Programme

This course will be held from March 13th to 31st, 2023.

Click here to download the detailed programme.

Registration

To register, please fill out the registration form. Within 24/72h, we will send you the confirmation and details for the payment. Please contact us if you do not receive a response in the next 5 days.

Target group

Post-Graduate students, Post-Doctoral Researchers and Group Leaders, with or without a background on cell culture.

Registration deadline

March 8th 2023

Fee

250,00 EUR

The fee includes

All the necessary material for the course
Certificate of attendance

Details for the payment

This information will be sent to the accepted participants.

Payment and invoicing policy

After submit the registration form, you will receive an email with the payment details (this may take up to 72 hours). To complete the registration process, you should proceed with the payment and send the receipt to upg-cursos@med.uminho.pt within 5 days.

Your registration will be effective after confirmation of the payment. If payment is not made in due time we will have to cancel the registration.

The correct indication of customer data during the payment, including a correct fiscal number, are the sole responsibility of the customer. y result from inaccurate information provided by the customer, particularly in the issuance of tax documents which are not susceptible to cancellation after issued. If you do not indicate the tax identification number you will be considered as final consumer (non-taxable person).

Cancelation and refund policy

You may cancel your registration at any time, but you will forfeit the full amount, irrespective of the date of cancellation. We cannot refund or return the fee, unless the course suffer any changes or it is cancelled.

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